Posts Tagged ‘Medication’
Friday, April 17th, 2009
Perhaps the most prescribed category of drugs for Alzhimer’s disease are the “Cholinesterase Inhibitor” branch. This group and grouping includes four medications. Their trade names are “Aricept” , “Cognex” , “Excelon” and “Reminyl”. This group of medications , specifically the “Cholinterase Inhibitors” work via a mechanism of raising brain levels of the chemical neurotransmitter in the brain , acetylcholine , that is deficient in people and patients who exhibit the signs , symptoms and progression of Alzheimer’s Disease and its variants.
It can be said that overall these drugs , and this classification of medications , work to slow the progression of Alzheimer’s Disease.
In terms of side effects , and the range and variations of side effects with the Cholinesterase classification of drugs side effects are all pretty similar in their type and range. This generally includes , nausea , vomiting ,diarrhea , stomach pain, and loss of appetite. However care must be exhibited with the drug / medication Cognex which can work to effect and cause liver toxicity and toxicities.
Dimebon Alzheimer?s Disease
http://www.dimebonalzheimers.com
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Tags: Acetylcholine, Aricept, Brain Levels, Chemical Neurotransmitter, Cholinesterase Inhibitor, Cholinesterase Inhibitors, Classification Of Drugs, Cognex, Diarrhea, Drug Medication, Drugs Effects, Liver Toxicity, Loss Of Appetite, Medication, Nausea Vomiting, Neurotransmitter In The Brain, Prescribed Drugs, Reminyl, Stomach Pain, Trade Names, Variants, Variations
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Sunday, March 15th, 2009
Dimebom is a new pharmaceutical treatment alternative for patients suffering from Alzheimer’s Disease. Dimebon is an older medication that has recently been discovered to be most helpful in treating patients with Alzheimer’s disease. Dimebom (the actual drug is known chemically as Dimebolin) is an older Russian antihistamine drug. It was popularly used in Russia as an antihistamine for hayfever, allergies and the like. In fact the drug was sold as an easy to obtain antihistamine – sold over the counter without a prescription.
Dimebom is currently in clinical trials in the United States by a company named Medivation . The website for Medivation, the pharmaceutical company involved with the clinical development and testing of Dimebom in the United States? Can be found at link www.medivation.com . To learn more about Medivation’s clinical trials of Dimebom the link is
http://www.medivation.com/pipeline_dimebontrials.html#p3
For more information on CONNECTION study locations, eligibility and enrollment, please visit www.connectionstudy.com or call toll-free 1-877-888-6386
At this point in time Dimebom is not available in any manner to Alzheimer Patients or their families, outside of the study material afforded by the Medivation Company and the Medivation clinical trials themselves.
Dimebon Alzheimer?s Disease
http://www.dimebonalzheimers.com
(more…)
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Tags: Allergies, Alzheimer Disease, Alzheimer S Disease, Antihistamine, Clinical Trials, Dimebon, Information Availability, Medication, Medivation, P3, Pharmaceutical Company, Pharmaceutical Treatment, Pipeline, Point In Time, Russia, Study Locations, Study Material, United States
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Monday, February 16th, 2009
Advantages of Razadyne ( galantamine) include that it may not as much disturb sleep and the sleep process in Alzheimer’s patients as the other mainstay medication of treatment of Alzheimer’s Aricept.
Common side effects of Razadyne include possible nausea , vomiting ,diarrhea ,fainting , loss of appetite and weight loss.? Most of these are mild and tend to subside as the body learns to adjust to the medication over time.
In M.C.I. trials Razadyne , thirteen ( 13) Razadyne recipients died, compared to only a single ( one) death among placebo patients – a finding that it seems of not many doctors are aware of.? Because more deaths occurred in the Razadyne group , than in the placebo group, doctors cannot rule out that the deaths were somehow related or due to Razadyne therapy.
Razadyne therapy can be initiated for patients with mild or moderate Alzheimer’s disease.
Dosage:? Razadyne? is supplied in both regular and extended release forms. Razadyne ER ( or SR designation slow- release formulation), can be taken once a day whereas Razadyne immediate release formulations are taken on a twice a da regime.? The two different formulations of Razadyne – immediate release and slow extended or sustained release formulations should not be taken together at the same time.? Its either one or the other since the active medication ingredient is the same.
The effective dose of Razadyne Extended Release (ER)? as well as immediate release ( regular) Razadyne? is stated to be in the ranges of 16 to 24 milligrams a day.? Doctors usually recommend starting with a lower initial dose of 8 milligrams a day and then increasing it to the lower maintenance dosage of 16 mg over a time span period of four ( 4) weeks. Then up according to the specific patients requirements and needs over a time span the dosage can be increased to upper stated limits of the drug.? Often patients can tolerate medications at higher levels if first started on a much lower initial dose and the dosage increased slowly over time.? The maxim is start lower and increase dosage slowly over time.
To reduce side effects , in terms of sleep disturbances and insomnia it is especially recommended to take the medication in the morning time with the extended release ER / SR form , and the taking of the second dose of the immediate release form somewhat earlier during the 24 clock of the daytime rather than later.
Dimebon Alzheimer?s Disease
http://www.psychiatry.co.il/
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http://www.dimebonalzheimers.com
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Tags: Alzheimer Disease, Alzheimer S Disease, Aricept, Deaths, Designation, Diarrhea, Galantamine, Immediate Release, Initial Dose, Loss Of Apetite, Loss Of Appetite, Mainstay, Medication, Milligrams, Moderate Alzheimer, Nausea, Placebo Group, Placebo Patients, Razadyne, Release Formulations, Single One, Slow Release Formulation, Time Span
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Thursday, February 12th, 2009
The medication? Razadyne was originally made from daffodil flowers using the very same extract that soldiers in ancient Greece used to stay alert on the battlefields.?? The drugs commercially available of Razadyne currently use a synthetic version or variant of this initial compound.
Radazyne not only blocks cholinesterase in the same way that the Alzheimer’s drug Aricept does but also and in addition stimulates the brain’s? nicotine and nicotinic receptors.? The nicotinic receptors in the brain serves the brain functioning and are involved in attention and learning facilities and functions and functioning.
Originally researchers had hoped that this double pharmacological actions would serve to double the drug’s benefits in treatment as well.
However clinical trials of Rasadyne ( chemically or generically galantamine) have not borne this out as well.
As a general guideline and measure Razadyne is generally held to be as effective in the ranges as that of Aricept.
Dimebon Alzheimer?s Disease
Dimebolin Dimebon Online Internet Pharmacies
http://www.dimebonalzheimers.com
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Tags: Alzheimer, Alzheimer Disease, Alzheimer S Disease, Ancient Greece, Aricept, Battlefields, Brain Functioning, Cholinesterase, Clinical Trials, Dimebon, Drugs, Flowers, Galantamine, Internet Pharmacies, Medication, Nicotine, Nicotinic Receptors, Pharmacologic, Pharmacological Actions, Razadyne, Synthetic Version
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Thursday, February 12th, 2009
What are the result of data on followup studies of patient’s taking and prescribed the aricept medication for the treatment of Alzheimer’s disease ?
Several studies ( some lasting as long as five (5) years)?? have ascertained and concluded that these patients declined and had their Alzheimer’s disease and cognitive symptoms declined at a slower rate than would of been expected? otherwise without therapy??? However these studies could be criticized as not being that well standardized or with a small patient count and being of short duration.
Dimebon Alzheimer?s Disease
Dimebolin Dimebon Online Internet Pharmacies
http://www.dimebonalzheimers.com
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Tags: Alzheimer, Alzheimer Disease, Alzheimer S Disease, Alzheimer Symptoms, Aricept, Aricept Medication, Cognitive Symptoms, Cunt, Duration, Followup Studies, Internet Pharmacies, Medication, Shrt, Term Followup
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Tuesday, February 3rd, 2009
Aricept was approved by the FDA for treating severe Alzheimer’s patients making it one of the few drugs indicated for all three stages of Alzheimer’s disease
Three preliminary studies have indicated and reported that patients who take Aricept have slightly less Alzheimer’s related loss in brain volume and volumes than those not being prescribed and taking the medication
A major three year study by the National Institutes of Health found that Aricept helped delay dementia for about eighteen months in patients with MCI.? At thirty six months, only a small subset of participants maintained these benefits. those with APOE4 gene , which increases a person’s risks of developing Alzheimer’s.
Aricept is one of the few CHeI studied exclusively in elderly African Americans with Alzheimer’s who had a similar response to others.? But because ethnic groups metabolize some drugs differently scientists view drugs in diverse ethnic groups more favorably.? At present most of the FDA approved meditations have been studied in Asians as well as Latin American ethnic groups.
Dimebon Alzheimer?s Disease
http://www.dimebonalzheimers.com
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Tags: Alzheimer, Alzheimer Disease, Alzheimer S Disease, American Ethnic Groups, Aricept, Array, Asians, Brain Volume, Chei, Dementia, Drugs, Fda, Institutes Of Health, Latin American, Mci, Medication, Meditations, National Institutes Of Health, Participants, Scientists, Six Months, Subset
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Monday, February 2nd, 2009
The question is often asked as to what is the “best ” dosage when it comes to the medication? Arciept.?? As with all medications there is no one “best ” dosage.? Dosages vary tremendously depending on the patient , their stage of the disease , what other medications they are taking currently and concurrently as well as a host of other factors.? Including in this equation is how much and for how long can the patient tolerate the drug to begin with.
What can be said easily? is what is the initial dosage and what are the “standard”? or usual dosages.
In the case of Aricept ten mg ( milligrams or thousandth’s of a gram) usually can be said to provide the most consistent benefits and is the usual standard optimal amount.
Doctors and Alzheimer’s patients medical teams ( under the direction and supervision of the captain of the team the physician), usually initiate Aricept treatments at a somewhat lower starting dose of 5 mg? once daily.
Then after a sutiable time period , usually in the ranges of four to six weeks increase the dose to that level of 10 milligrams.
Both fice (5) milligrams and 10 mg daily are effective, and thus people and patients who cannot tolerate 10 milligrams may tolerate 5 mg and thus remain on a dose that they can both tolerate and that they can ultimately benefit from.? In some of these cases , after a somewhat longer or even lengthy time period , the patient may go on to be able to tolerate the higher ten mg a day doseage and benefit from this level as well.
It should be noted that in very frail people or those with major concerns about side effects, the Aricept dosage can be started at an even lower dosage than the 5 mg a day , by providing for administration of the Aricept medication on alternate days.? Usually taken with dinner or breakfast ( to tie in with a daily habit in order to increase medication compliance by the patient).? As well as tablet forms Aricept is also available as an orally Disintegrating tablet format .? This dissolves in the mouth and does not need to be directly or mechanially swallowed.? Many patients do have problems when it comes to swallowing pills and tablet intact.
Dimebon Dimebolin Alzheimer’s
http://www.dimebonalzheimers.com/
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Tags: Alternate Days, Alzheimer, Aricept, Aricept Dosage, Aricept Medication, Direction, Doctors, Habit, Initial Dosage, Lengthy Time, Medical Teams, Medication, Medication Compliance, Medications, Milligrams, Six Weeks, Supervision, Time Period
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Thursday, January 29th, 2009
Common Side Effects of Aricept ( generically known as doneperzil) , include possible nausea, vomiting , diarrhea, bruising, fainting , insomnia or “not sleeping well”, loss of appetite, feeling tired and finally possibility of muscle cramps and cramping.
Most of these side effects could be said to mild and tend or tended to subsidize as the body adjusts to the medication over a number of days or extended time period .? Aricept may be more likely than Exelon or Razadyne to cause mild sleep problems such as vivid dreams as well as possible nocturnal illusions.? Urinary problems? are often occasionally seen with the use of Aricept.
Dimebon Alzheimer?s Disease
dimebon online pharmacy
http://www.dimebonalzheimers.com
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Tags: Alzheimer, Alzheimer Disease, Alzheimer S Disease, Aricept, Diarrhea, Dimebon, Exelon, Insomnia, Loss Of Appetite, Medication, Muscle Cramps, Nausea, Nocturnal Illusions, Online Pharmacy, Razadyne, Sleep, Sleep Problems, Time Period, Urinary Problems, Vivid Dreams
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Thursday, January 29th, 2009
Aricept can be said to have been studied longer , and in more patients two similar medications or so that are in present medical and pharmaceutical use.? Aricept is the easiest to use of the pharmaceutical choices and is often noted as being the best tolerated by patients over the alternative treatments.?? Aricept clears more slowly than the other drugs from the body.? Shorter half lives or longer half lives for drugs have both good and bad points in consideration of the treatment choice for the specific patient and treatment plan in view.
Compliance ( the percent of the time that patients take the medication as prescribed or recommended? properly as described is estimated generally at 50 %).??? The “studies”? show and demonstrate that little can be done to improve compliance levels of drugs, other than making the treatment regime easier? and less complex , or to tie in the taking of the pills , tablets , liquid or whatever the form the medication is in? with a daily habit of the patient – say a meal or shaving time in the morning.?? The other way to enhance compliance is to make the regimen simpler – say for example by making the medicine choice 2 times a day instead of 4 times a day.
With medications with a longer half life if the patient does mean taking a dose, there is still some drug or drug levels left in the body.Hence the drug will stay be in the body and serum to some level .? This is an advantage for the drug Aricept.? On the other side of the fence if side effects are a problem these side effects will last longer and take a longer time to clear.? Often though one way of dealing with this is to start with lower dosages initially in the first time periods.? On top of that patients can often get “used to a drug”? taken this way , starting off with lower dosages rather than blasting the patient from the beginning.? Started at lower levels and dosages initially patients can often be treated with medications and medication dosages that side effects would limit otherwise. On top of that most Alzheimer patients are being treated with a range of multitude of different drugs and medications already whose side effect interactions are often unstudied or unknown or both.
Only one dose of the drug Aricept is needed as a standard dose per day.? Its a fairly simple regimen.? Aricept as a result is widely used for Alzheimer’s patients.? Its benefits for Alzheimer’s patients can last up to a year.
Dimebon Alzheimer?s Disease
http://www.dimebonalzheimers.com
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Tags: Alternative Treatments, Aricept, Choices, Compliance Levels, Drugs, Habit, Half Life, Half Lives, Medication, Medication Dosages, Medications, Medicine, Pills, Regimen, Serum, Shaving Time, Side Of The Fence, Time Periods, Treatment Choice, Treatment Regime
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Wednesday, January 14th, 2009
Dimebon ( chemically or the generic term Dimebolin) has attracted a fair amount of attention both in the medical , lay and popular press. The options available for the treatment of Alzheimer’s patients are limited , the disease is so devastating , so that any new therapies or newer therapies that invoke hope are well received.
The problem basically with any new drug , medication or formulations introduced to the marketplace boil down basically to one of numbers and drug interactions. Any medication that is released to the marketplace is basically and essentially only tested on a relatively very small group of patients / victims.
Its not that the testing process is slipshod. It is not and is well is very expensive. Its just that the numbers are relatively small in limited situations. The first thing that is always tested for is safety. If the drug is inherently unsafe then the whole process should be stopped. This potentially does not come into play if the drug will save some people in a situation where nothing else will. Everything in life of course , always comes to risks vs benefits.
The basic problem with drug testing and introduction is simply a matter of numbers , percentages , and interactions with medications or other agents not thought of , or not tested.
It all boils down to statistics and numbers. 1/100 of a percent involving a trial with 100 or even 1000 patients may not uncover damming side effects whereas if that same product is released into the marketplace , with millions of users and patients , and whammo that terrible side effect comes to light now . Not only that when multiplied out , the amount of patients affected adversely is not small , and is indeed large and troubling. The question will be why these interactions and side effects not found , noticed or detected before ?
Which brings up to the beauty of this specific chemical / medication to be used in the treatment of Alzheimer’s Disease.
Dimebon or Dimbolin is an older antihistamine drug which was used in Russia / U.S.S.R. as a widely available medication that was used in great numbers and prevalence for a good period of time. The drug was widely used as it was available easily and widespread without even a prescription. There do not appear to have enough problems with the medication that many problems seem to have be reported with its use.
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dimebon is cure of alzheimer?s disease? – recently dimebolin has sparked renewed interest after being shown to have positive effects on people suffering from alzheimer?s disease. animal studies showing the potential beneficial effects on alzheimer?s disease models were …
comfort for the afflicted – for example, the antihistamine dimebolin hydrochloride preserved cognition in an 18-month investigation. and the antimalarial methylthioninium chloride interfered with the accumulation of tau tangles in the brain in an 84-week study. …
Pfizer pays $725 Million for experimental drug (Life, Liberty, and … – Pfizer said that it was acquiring the rights to a new experimental substance aimed to help Alzheimer’s disease. The substance (Pictured Above) is Dimebolin, a antihistamine that works on the AMPA/NMDA receptors. …
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http://www.dimebonalzheimers.com
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Tags: Alzheimer Disease, Alzheimer S Disease, Antihistamine, Current Research, Dimebon, Drug Interactions, Drug Medication, Drug Testing, Marketplace, Medication, Percentages, Popular Press, Small Group, Statistics, Whammo
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