Archive for February, 2009

Increased Death Rates During Aricept Trials

Monday, February 9th, 2009

When used for people with vascular dementia , Aricept generally improves thinking and the thought processes.?? During one study , the apparent concerns? was that the death rate and rates were scored higher than those not taking the drug.?? It seemed that those patients taking Aricept had a greater chance of dying than those taking the placebo , the inert sugar pills.

With careful statistical analysis it appears that the pattern was not prevalent or repeatable.? What this means that this count of increased chance of death, while taking Aricept, as a treatment for Alzheimer’s Disease was not repeatable or predictable when the study was repeated in a similar manner. The cause of this one report of increased death rates appears to be an anomaly or a one time chance untimely event – a coincidence with no known cause or effect that did nto happen again or any regular basis.

Dimebon Alzheimer?s Disease

http://www.dimebonalzheimers.com

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Arcicept Studies Information

Tuesday, February 3rd, 2009

Aricept was approved by the FDA for treating severe Alzheimer’s patients making it one of the few drugs indicated for all three stages of Alzheimer’s disease

Three preliminary studies have indicated and reported that patients who take Aricept have slightly less Alzheimer’s related loss in brain volume and volumes than those not being prescribed and taking the medication

A major three year study by the National Institutes of Health found that Aricept helped delay dementia for about eighteen months in patients with MCI.? At thirty six months, only a small subset of participants maintained these benefits. those with APOE4 gene , which increases a person’s risks of developing Alzheimer’s.

Aricept is one of the few CHeI studied exclusively in elderly African Americans with Alzheimer’s who had a similar response to others.? But because ethnic groups metabolize some drugs differently scientists view drugs in diverse ethnic groups more favorably.? At present most of the FDA approved meditations have been studied in Asians as well as Latin American ethnic groups.

Dimebon Alzheimer?s Disease

http://www.dimebonalzheimers.com

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"Best' Dosage of Aricept ?

Monday, February 2nd, 2009

The question is often asked as to what is the “best ” dosage when it comes to the medication? Arciept.?? As with all medications there is no one “best ” dosage.? Dosages vary tremendously depending on the patient , their stage of the disease , what other medications they are taking currently and concurrently as well as a host of other factors.? Including in this equation is how much and for how long can the patient tolerate the drug to begin with.

What can be said easily? is what is the initial dosage and what are the “standard”? or usual dosages.

In the case of Aricept ten mg ( milligrams or thousandth’s of a gram) usually can be said to provide the most consistent benefits and is the usual standard optimal amount.

Doctors and Alzheimer’s patients medical teams ( under the direction and supervision of the captain of the team the physician), usually initiate Aricept treatments at a somewhat lower starting dose of 5 mg? once daily.

Then after a sutiable time period , usually in the ranges of four to six weeks increase the dose to that level of 10 milligrams.

Both fice (5) milligrams and 10 mg daily are effective, and thus people and patients who cannot tolerate 10 milligrams may tolerate 5 mg and thus remain on a dose that they can both tolerate and that they can ultimately benefit from.? In some of these cases , after a somewhat longer or even lengthy time period , the patient may go on to be able to tolerate the higher ten mg a day doseage and benefit from this level as well.

It should be noted that in very frail people or those with major concerns about side effects, the Aricept dosage can be started at an even lower dosage than the 5 mg a day , by providing for administration of the Aricept medication on alternate days.? Usually taken with dinner or breakfast ( to tie in with a daily habit in order to increase medication compliance by the patient).? As well as tablet forms Aricept is also available as an orally Disintegrating tablet format .? This dissolves in the mouth and does not need to be directly or mechanially swallowed.? Many patients do have problems when it comes to swallowing pills and tablet intact.

Dimebon Dimebolin Alzheimer’s

http://www.dimebonalzheimers.com/

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